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Hemoglobin interactions and whole blood oxygen equilibrium curves in sickling disorders.
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Hydrea is contraindicated in patients who have demonstrated a previous hypersensitivity to hydroxyurea or any other component of the formulation.
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The homeopathic preparation Vertigoheel versus Ginkgo biloba in the treatment of vertigo in an elderly population: a double-blinded, randomized, controlled clinical trial.
Prevalence of daily medication adherence among children with sickle cell disease: A 1-year retrospective cohort analysis.
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We searched the Cochrane Injuries Group Specialized Register, CENTRAL (Cochrane Central Register of Controlled Trials), MEDLINE from 1950 to the second week of August 2009, EMBASE from 1980 to the fourth week of 2011, SCI-EXPANDED (Science Citation Index Expanded) from 1970 to February 2011, and CPCI-S (Conference Proceedings Citation Index-Science) from 1990 to February 2011.
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More severe side effects include reduction of white blood cells (neutropenia) and the cells responsible for normal blood clotting (thrombocytopenia).
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ASA: aspirin; HU: hydroxyurea; ANA: anagrelide; TIA: transient ischemic attack; AMI: acute myocardial infarction; VTE: venous thromboembolism.
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The dependent variables are: SF-36 Health Status Survey variables (as a percent scores), Mood Profile, Ladder of Life.
It is important not to become pregnant or father a child while you are having treatment with this drug and for a few months afterwards.
Treatment options include hydration, high-dose antibiotics for resulting pyelonephritis, and possible percutaneous nephrostomy tube or invasive retrieval of sloughed papillae in acute urinary obstruction.
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The psychosocial dynamics of sickle cell disease are complex.
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Likewise, aspirin may not be recommended for patients on other medications such as blood thinners that increase the risk of bleeding.
Although hematologic changes indicative of SCD are evident as early as the age of 10 weeks, symptoms usually do not develop until the age of 6-12 months because of high levels of circulating fetal hemoglobin.
Among 51 patients with polycythemia vera who were treated with hydroxyurea and who had received no prior therapy, leukemia developed after treatment in 3 (5.
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Repair of DNA damaged by chemicals or irradiation is also inhibited by hydroxyurea, offering potential synergy between hydroxyurea and radiation or alkylating agents.
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Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
The log-rank statistic was used to compare distributions.
Providers who prescribe opioids for patients with sickle cell pain must be cognizant of the current legal requirements.
Low Dose Hydroxyurea is Effective in Reducing the Incidence of Painful Crisis and Frequency of Blood Transfusion in Sickle Cell Anemia Patients from Eastern India.
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The examination of the function of the liver using biochemical tests, radiologic procedures, or liver tissue samples.
The expert panel and methodology team identified existing systematic reviews and clinical practice guidelines that were relevant to the topics of this guideline, even though they were not necessarily specific to people with SCD.
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Strategies of chelation using a combination of desferrioxamine and deferiprone have been effective in individuals with severe iron overload.
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Blood mononuclear cells and platelets have abnormal fatty acid composition in homozygous sickle cell disease.
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But this clinical trial was very small and so we need further research to know whether homeopathy really has an effect.
Other heart diseases include congestive heart failure, heart rhythm problems, congenital heart disease (heart disease at birth), and endocarditis (inflamed inner layer of the heart).
There is still no cure for sickle cell disease other than experimental transplantation procedures, but treatments for complications of sickle cell have prolonged the lives of many patients who are now living into adulthood.
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The absence of a warning for a given drug or drug combination in no way should be construed to indicate that a drug or drug combination is safe, effective or appropriate for any given patient.
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Kater AP, Hejboer H, Peters M, Vogels T, Prins MH, Heymans HS: Quality of life in children with sickle cell disease in Amsterdam area (Dutch) Netherlands.
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