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I have had Polycythemia vera for 25 years. I was started on hydroxyurea two months ago and recently developed severe petechial hemorrhaging. I was admitted to the hospital with a platelet count of 9,000. I received a six pack of platelets and over seven days (being off the medication) my platelet count had climbed to 74,000. As of Sunday, July 5th, it was at 139,000 (off the medication for ten days). I was given the medication to help prevent the POTENTIAL of developing a blood clot. I have managed my Polycythemia vera pretty well without medication for 25 years (I do take baby aspirin) and wish I had never taken this.

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However, this determination was based on conditional haplotype tests that excluded uninformative haplotypes.

Anagrelide is an imidazoquinazoline drug that inhibits platelet aggregation.

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Tirapazamine is commonly used in combination with cisplatin-based chemoradiotherapy, but remains investigational.

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The lack of therapeutic benefit of adding hydroxyurea to highly active antiretroviral therapy (HAART).

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These secondary stroke prevention guidelines include recommendations for controlling risk factors and the use of antiplatelet agents.

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While you are being treated with hydroxyurea, and after you stop using it, do not have any immunizations (vaccines) without your doctor's approval.

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Hydroxyurea is a medicine generally used to treat cancer.

SCD may not yet be able to identify how to effectively balance rest and exercise, so parents need to manage this.

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Disseminated granuloma annulare may be persistent, lasting for as few as 3 years but in some cases up to 10 years.

Do not drive or operate heavy machinery until you know how this medication affects you.

However, all regimes have issues with compliance and side effects that require appropriate monitoring.

Gold may cause blue-grey pigmentation in light-exposed areas (chrysiasis) silver may cause a similar discoloration (argyria) Lead poisoning can cause a blue-black line at the gingival margin and grey discoloration of the skin.

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Pseudoxanthoma elasticum is a disease of elastic tissue characterized by generalized fragmentation and progressive mineralization of the elastic fibers in various tissues, involving the dermis (flexural sites), eye (angioid streaks) and cardiovascular system (hypertension and gastrointestinal bleeding).

Population screening associated with genetic counseling is extremely useful by allowing couples at risk to make informed decision on their reproductive choices.

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Surveys indicate that a large proportion of patients who have sickle cell disease are poor and from underserved communities.

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This abnormal shape causes the red blood cells to be stiff and sticky, making it difficult for them to move throughout the body.

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Patients continued using SMART to record clinical symptoms, pain intensity, location and perceived severity, and treatment strategies for at least 28 days.

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Oxygen therapy is often used routinely in the management of vaso-occlusive crises, despite lack of evidence supporting the effectiveness of these measures in all patients.

Check with your doctor immediately if you notice any unusual bleeding or bruising; black, tarry stools; blood in the urine or stools; or pinpoint red spots on your skin.

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Confirmatory tests, such as a duplex ultrasound, may be performed and can be helpful.

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They also show that it does not cause resistance while somehow increasing the activity of some antiviral drugs against drug-resistant strains of the virus.

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HMG-CoA reductase inhibitor drugs are called statins.

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Hydroxyurea is hydroxylated analogue of urea and suppresses DNA replication by inhibition of ribonucleotide reductase, a necessary step in deoxyribonucleic acid synthesis; its hepatic metabolism is not well characterized, but is probably via the cytochrome P450 system; discussion of side effects mentions liver enzyme elevations).

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Psoralen is typically taken by mouth in the form of 8-methoxypsoralen (for example, Oxsoralen) 75 minutes to 2 hours before the treatment starts.

Hydroxyurea is a chemotherapy agent used in veterinary medicine for the treatment of certain solid, myeloid tumors as well as treatment for polycythemia vera, a blood disorder.

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It is a cytotoxic agent, and has the potential to cause life-threatening cytopenia.

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Patients with sickle cell disease are often poorer than the national average and are more often covered by Medicaid.

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